The World Bank defines the Blue Economy as the sustainable and integrated development of economic sectors in healthy oceans. It is a framework to realize the Sustainable Development Goals (SDGs), address climate change, reduce biodiversity loss, and provide opportunities for shared prosperity for all. Volume 1, Key Considerations to Formulate and Implement Marine Spatial Planning, details how to realize the Blue Economy using marine spatial planning (MSP). The World Bank can employ these plans to generate public and private investments while contributing to green, resilient, and inclusive growth (GRID). To succeed, MSP needs to consider not just the process, but other cross-cutting issues and themes, which can vary depending on local circumstances. Cross-cutting considerations are additional issues or themes that intersect the MSP process or are easily integrated without losing focus on the formulation and implementation of a marine spatial plan. These are the focus of the current document, Volume 2. It is important to consider or integrate cross-cutting issues and themes into MSP in order to: ensure that the process is inclusive, fair, and transparent. use good data and tools to objectively inform decision making. enable planners and stakeholders to formulate a climate-informed marine spatial plan that balances biodiversity and ecosystem services among current and future uses. provide a framework that assesses and improves the performance of MSP and captures lessons learned. The most common cross-cutting considerations in MSP are stakeholder engagement, data and tools, gender equality and women’s empowerment, climate change, biodiversity and ecosystem services, and monitoring and evaluation. These considerations are the focus of this Volume.